As a territory of the US, the US Government has responsibility for American Samoa's foreign relations. American Samoa is a member of the Pacific Community (SPC) and the South Pacific Regional Environmental Program (SPREP).

American Samoa and the neighbouring Independent State of Samoa have close cultural, historical and community links. The Governor of American Samoa and the Prime Minister of Samoa hold regular meetings to discuss matters of mutual concern, such as the movement of people (with many Samoan nationals working in American Samoa's tuna processing plants).